Intawat Nookaew, PhD Department of Chemical and Biological Engineering, Chalmers University of Technology, Kemivägen 10, SE-412 96 Göteborg, Sweden Phone: +46(0)31 772 3854 Fax: +46(0)31 772 3801 E-mail: intawat [at] chalmers.se Office: Room 3056A     Education and degrees 2000 B.Eng. in Chemical Engineering, Suranaree University of Technology, Nakhon Ratchasima, Thailand 2008 Ph.D. in Chemical Engineering, Mongkut’s University of Technology Thonburi, Bangkok, Thailand  Employments 2005-2006 Visiting Doctoral Research at Center form Microbial Biotechnology (CMB), Technical University of Denmark, Lyngby, Denmark 2007-2008 Researcher, Pilot Plant Development and Training Institute, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand 2008-2010 Post doc, Department of Chemical and Biological Engineering, Chalmers 2010- Project Leader, Systems and Synthetic Biology, Department of Chemical and Biological Engineering, Chalmers Publications, Patents & Presentations Publications 2007 Nookaew, I., Meechai, A., Thammarongtham, C., Loateng, K., Ruanglek, V., Cheevadhanarak, S., Nielsen, J., and Bhumiratana, S. Identification of flux regulation coefficients from elementary flux modes: A systems biology tool for analysis of metabolic networks. Biotechnol. Bioeng. Vol 97, No. 6, p1535-1549 2008 Nookaew, I., Jewett, M.C., Meechai, A., Thammarongtham, C., Loateng, K., Cheevadhanarak, S., Nielsen, J., and Bhumiratana, S. The Genome-scale Metabolic Model iIN795 of S. cerevisiae and Its Validation: a scaffold to query lipid metabolism. BMC Systems Biology, Vol 2, No.72 2010 Vonsangnak, W., Nookaew, I., Salazar M.,  Nielsen J. (2010) Analysis of genome-wide co-expression and co-evolution of Aspergillus oryzae and Aspergillus niger. OMICS doi:10.1089/omi.2009.0118   Cvijovic, M., Olivares-Hernández, R., Agren, R., Dahr, N.,Vongsangnak, W., Nookaew I., Patil, K.P.,  Nielsen, J, BioMet Toolbox: genome-wide analysis of metabolism. Nucleic Acids Res. 2010 Jul 1;38   Papini, M., Nookaew, I., Scalcinati, G., Siewers, V.,  Nielsen J. (2010) Physiological investigation and transcriptome analysis of a Saccharomyces cerevisiae phosphoglycerate mutase knock-out mutant. Biotechnol J. 2010 Oct;5(10):1016-27.   Nookaew, I#., Gabrielsson B.G.#, Holmäng, A., Sandberg, A-S.,  Nielsen, J., (2010) Identifying molecular effects of diet through systems biology : Influence of herring diet on sterol metabolism and protein turnover in mice. PLoS One. 2010 Aug 24;5(8):e12361   Bordel S., Nookaew I., (2010) Systems biology or just biology? A report of the 11th International Conference on Systems Biology 2010 Dec;5(12):1257-60 2011 Karlsson F.H., Ussery D.W., Nielsen J., Nookaew I.* (2011) A Closer Look at Bacteroides: Phylogenetic Relationship and Genomic Implications of a Life in the Human Gut. Microb Ecol. 2011 Jan 11   Karlsson F.H., Nookaew I., Petranovic D., Nielsen J. (2011) Prospects for systems biology and modeling of the gut microbiome. Trends Biotechnol. In press   Lindqvist M#, Nookaew I#, Brinkenberg I, Samuelson E, Thörn K, Nielsen J, Harandi AM. (2011) Unraveling molecular signatures of immunostimulatory adjuvants in the female genital tract through systems biology. PLoS One. 2011;6(6):e20448. Epub 2011 Jun 7   Osterlund T, Nookaew I, Nielsen J. (2011) Fifteen years of large scale metabolic modeling of yeast: Developments and impacts. Biotechnol Adv. 2011 Aug 6.   Larsson E., Fricker A., Tremaroli V., Lee Y.S., Nookaew I., Nielsen J., Ley R.E., Bäckhed F. (2011) MyD88-dependent signaling modulates virus susceptibility and gut microbial ecology. GUT.Nov.2011 2012 Papini M., Nookaew I., Siewers V., Nielsen J.,(2012) Physiological characterization of recombinant Saccharomyces cerevisiae expressing the Aspergillus nidulans phosphoketolase pathway: validation of activity through 13C-based metabolic flux analysis. Accepted Applied Microbiology Biotechnology. Book Chapters 2007 Nookaew, I., Olivares-Hernández, R., Bhumiratana, S., Nielsen, J. Genome-scale metabolic models of Saccharomyces cerevisiae. State-of-the-art (chapter 3). Yeast Systems Biology, Humana press. Conference Proceedings 2002 Tiyasantiwong, J., Nookaew, I., Meechai, A., Thammarongtham, C., Cheevadhanarak, S., and Bhumiratana, S. (2002) Elementary mode analysis of fatty acid biosynthetic pathways in Mycobacterium tuberculosis: in quest of potential drug targets. At the 14th annual meeting of the Thai Society for Biotechnology, ‘Biotechnology for better living in the new economy’ 12-15, Thailand   Nookaew, I., Liamprawat, C., Meechai, A., Laoteng, K., Cheevadhanarak, S., and Bhumiratana, S. (2002) Topology analysis of fatty acid metabolism in Saccharomyces cerevisiae, Chemical Engineering and application conference, Thailand   Nookaew, I., Liamprawat, C., Meechai, A., Laoteng, K., Cheevadhanarak, S., and Bhumiratana, S. (2002) Elementary flux mode analysis of fatty acid metabolism in Saccharomyces cerevisiae.  The International Conference on Bioinformatics 2002: North-South Networking, Thailand. 2003 Meechai, A., Nookaew, I., Thamarongtham, C., Laoteng, K., Ruanglek, V., Cheevadhanarak, S., and Bhumiratana, S. (2003) Pathway analyses of yeast metabolic reaction network for potential improvement of fatty acids production. at the 6th Asia Pacific Biochemical Engineering Conference 03,Australia. Poster Presentations 2002 Sukarrom, N, Nookaew, I., Meechai, A., Thammarongtham, C., Cheevadhanarak, S., Bhumiratana, S., (2002),"Construction of in silico strain of Mycobacterium tuberculosis H37Rv", At the 14th annual meeting of the Thai Society for Biotechnology, ‘Biotechnology for better living in the new economy’ , Khon Kaen, Thailand   Direksoonthorn, S., Nookaew, I., Meechai, A., Thammarongtham, C, Laoteng, K., Ruanglek, V., Cheevadhanarak, S., Bhumiratana, S.,(2002) "Construction of computational yeast model by using flux balance analysis", At the 14th annual meeting of the Thai Society for Biotechnology, ‘Biotechnology for better living in the new economy’, Khon Kaen, Thailand.   Nookaew, I., Meechai, A., Laoteng, K., Thammarongtham, C, Cheevadhanarak, S., Bhumiratana, S.,(2002), "Potential improvement of fatty acids production in Saccharomyces cerevisiae by elementary flux mode analysis", At the 14th annual meeting of the Thai Society for Biotechnology, ‘Biotechnology for better living in the new economy’ , Khon Kaen, Thailand. 2003 Ruanglek, V., Nookaew, I., Meechai,  Cheevadhanarak, S., Bhumiratana, S. (2003), Effect of Temperature on Growth and Fatty Acids Production in Saccharomyces cerevisiae BY4742", BioThailand, Pattaya, Thailand.   Nookaew, I., Meechai, A., Laoteng, K., Thammarongtham, C, Cheevadhanarak, S., Bhumiratana, S. (2003), "Metabolic flux analysis of glucose-6-phosphate dehydrogenase deficient Saccharomyces cerevisiae strain", BioThailand, Pattaya, Thailand. 2004 Nookaew, I., Meechai, A., Vorapreeda, T., Ruanglek, V., Thammarongtham, C., Cheevadhanarak,  S., Bhumiratana, S. and Laoteng, K. (2004). Exploring the effect of flux through pentose phosphate pathway on fatty acids biosynthesis of Saccharomyces cerevisiae by metabolic flux analysis, Beyond Genome 2004, 21-24 June, Fairmont Hotel, San Francisco, USA. 2006 Jewett M.C., Nookaew I., Pizarro F.A., Hellgren L.I., Agosin E, Nielsen J.,(2006), Exploring Biosynthetic Control in Lipid Metabolism, AIChE annual meeting 2006,San Francisco Hilton, San Francisco, USA. 2007 Saerue S., Nookaew I., Boonthongchuay A., Meechai A., Cheevadhanarak S., Bhumiratana S. Exploring Predominant Metabolic Processes during a Light-Dark Cycle. BioAsia : “Technology for Self Sufficient Agriculture in Asia”, Bangkok, Thailand. 2008 Nookaew, I., Meechai, A., Thammarongtham, C., Loateng, K., Cheevadhanarak, Bhumiratana S., Nielsen, J. (2008), Mapping regulatory mechanisms of Saccharomyces cerevisiae lipid metabolism., International Conference on Systems Biology (ICSB), Gothenburg, Sweden. Teaching Experience Experience from teaching at Master’s level 3 years and on Doctoral courses 1 year Tutoring Experience Co-supervisor of PhD students 9 Co-supervisor of MSc students 5 Grants, Awards and Prizes Ph.D. Scholarship, Thai Graduate Institute of Science and Technology (TGIST) Knut and Alice Wallenbergs foundation travel awards National Institute of Health (NIH) travel awards Personal text Systems Biology now is very promising and challenge in many areas.  I am a person who believes in systems biology science.  So I decide to start working in this group to gain my knowledge and experiences in this field. Right now I have focus on mathematical modelling of human metabolism and omics data integration analysis as well as biological network analysis. I hope that my focused work will lead to better understanding the cause of human diseases (e.g. cancer, obesity, diabetes) and affect of nutrition on human health.