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Luis Caspeta, PhD
Department of Chemical and Biological Engineering,
Chalmers University of Technology,
Kemivägen 10, SE-412 96 Göteborg, Sweden
Phone: +46(0)31 772 3846
Fax: +46(0)31 772 3801
E-mail: luisc [at] chalmers.se
Office: Room 3056B |
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Education and degrees
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| 2000 |
Chemical Engineering, Autonomous University of Morelos State, UAEM, México |
| 2005 |
M.Sc. in Biotechnology, Biotechnology Research Center, UAEM, México |
| 2009 |
Ph.D. in Biochemical Sciences, Institute of Biotechnology, UNAM, México |
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Employments |
| 2000-2002 |
Technical Assistant, Northwest Electronic Controls, Cuauhtémoc-Moctezuma Brewery, Mexico |
| 2005-2009 |
PhD student, Institute of Biotechnology, UNAM, México |
| 2009-2010 |
Post doc, Institute of Biotechnology, UNAM, México |
| 2010- |
Post doc, Department of Chemical and Biological Engineering, Chalmers |
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Publications, Patents & Presentations |
| Publications |
| 2005 |
Caspeta L, Quintero R, Villarreal MaL. 2005. Novel airlift reactor fitting for hairy root cultures: developmental and performance studies. Biotechnol Prog, 21: 735-740. |
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Caspeta L, Nieto I, Zamilpa A, Alvarez L, Quintero R, Villarreal MaL. 2005. Solanum chrysotrichum hairy root cultures: characterization, scale-up and production of five antifungals for human use. Planta Medica, 71: 1084-1087. |
| 2008 |
Lara AR, Caspeta L, Gosset G, Bolívar F, Ramírez OT. 2008. Utility of an Escherichia coli strain engineered in the substrate uptake system for improved culture performance at high glucose and cell concentrations: an alternative to fed-batch cultures. Biotechnol and Bioengin, 99: 983-901 |
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Villarreal Ma L. Caspeta L, Quintero R. 2008. From the Mayan highlands to the bioreactors: In vitro tissue culture of the Mexican medicinal plant Solanum chrysotrichum. Electronic Journal of Integrative Biosciences 3: 20-28. |
| 2009 |
Caspeta L, Flores N, Pérez NO, Bolívar F, Ramírez OT. 2009. The effect of heating rate on Escherichia coli metabolism, physiological stress, transcriptional response, and production of temperature-induced recombinant protein: a scale-down study. Biotechnol and Bioengin, 102: 468-482.
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| 2010 |
Valdez-Cruz NA,Caspeta L, Ramírez OT, Perez NO, Trujillo-Roldán MA. Production of recombinant proteins in E. coli by the heat inducible expression system based on the phage lambda pL and/or pR promoters. Microb Cell Fact, 9:18. |
| 2011 |
Soto R, Caspeta L, Barrón B, Gosset G, Ramírez OT, Lara AR. High cell-density cultivation in batch mode for plasmid DNA vaccine production by a metabolically engineered E. coli strain with minimized overflow metabolism. Vaccine, submitted. |
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Lara AR, Knabben I, Regestein L, Sassi J, Caspeta L, Ramírez OT, Büchs J. Pressurized cultivation: a viable option to increase oxygen transfer and to scale-up plasmid DNA production fermentations. Engineering in Life Sciences, submitted.
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| Talks |
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4
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Invited seminars at universities |
2
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Oral presentations at international conferences |
7
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Oral presentations at domestic conferences |
Poster presentations |
5
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Poster presentations at international conferences |
2
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Poster presentations at domestic conferences |
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| Teaching and Tutoring Experience |
| Co-supervisor of undergraduate students |
2 |
| Co-supervisor of master students |
2 |
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| Grants, Awards and Prizes |
| 2002-2004 |
Master scholarship from CONACYT-Mexico |
| 2005-2009 |
PhD scholarship from CONACYT-Mexico |
| 2005 |
Diploma for the best dissertation in Master Studies |
| 2009 |
Honour mention to the Ph.D. dissertation |
| 2010- |
Member of the National Researchers System (SNI –in Spanish- level of candidate) |
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| Personal text |
The production of valuable molecules is subjected to complex interactions between cells genotype and the environment inside the bioreactor. During my postgraduate studies, I was interested in the optimization of the fermentation processes on the base of the knowledge of such relations. Now, I am convinced that the plethora of interactions may be only understood by using the integrative approach of the systems biology. At the present, I am working in the genome-scale reconstruction of metabolic networks and their constraint base simulations. |
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