Systems and Synthetic Biology is headed by Professor Jens Nielsen and is composed of several labs and faculty. Each lab has a leader who is responsible for directing particular research themes. The lab and computational facilities are shared among all members of Systems and Synthetic Biology.
Systems and Synthetic Biology has a central role in LifeScience@Chalmers, which is one of eight Areas of Advance at Chalmers University of Technology. The director of Life Science Engineering Area of Advance is Professor Ivan Mijakovic.
We are interested in understanding and using the dynamic behavior of signal transduction pathways.
Our lab is focused on understanding the physiology and metabolic regulation in the yeast Saccharomyces cerevisiae and to apply this knowledge in various metabolic engineering projects.
We work on signaling and regulation in bacterial cells, focusing in particular on regulatory phenomena based on protein phosphorylation.
Our research focus is on systems biology of metabolism. The yeast Saccharomyces cerevisiae is our key organism for experimental research.
We are combining methods of molecular and cell biology, biochemistry, bioinformatics and systems biology with the scope to study how cells regulate aging and death pathways.
Leif Väremo’s thesis entitled “Systems Biology of Type 2 Diabetes in Skeletal Muscle” was selected as the best preclinical thesis by the Swedish Diabetes Association.
Jens Nielsen was appointed as Adjunct Professor at Jiangnan University, Wuxi, China
Through sequencing 10 penicillia genome SysBio identified a large number of new secondary metabolite biosynthetic gene clusters were identified. The study was published in Nature Microbiology and featured in Cosmos Magazine.
Paper published in Nature Chemical Biology about engineering the yeast fatty acid synthase for production of short chain fatty acids by yeast was covered by more than 30 newspapers around the world