Phone:+46 (0)70 982 8446
E-mail: Ivan.Mijakovic [at] chalmers.se
Office: Room 3056A (Fysik Origo, Kemigården 1)
We are interested in signaling and regulation in bacterial cells, focusing in particular on regulatory phenomena based on protein phosphorylation. Most of our research activities are carried out on Bacillus subtilis, a model organism for Firmicutes. B. subtilis is a wonderful model for studying complex signaling circuits in developmental phenomena, since it displays a wide array of “survival” strategies: motility, versatile degradative functions, production of bacteriocins, natural competence, biofilm formation, cannibalism and spore development. Our laboratory specializes in bacterial protein-tyrosine kinases (BY-kinases), serine/threonine kinases of the Hanks-family, phosphoproteomics other “omics” approaches aiming at global studies of the phosphorylation-based regulatory networks in both model and pathogenic bacteria. We are also interested in the evolution of protein kinases and their relationship with substrates.
In collaboration with the Chalmers Graphene Centre, we are developing advanced graphene-based antibacterial coatings, bio-sensors and procedures for extraction of oleochemicals from microbial cell factories.
We are implementing a wide array of metabolic engineering tools in order to optimize B. subtilis as a cell factory for the production of platform chemicals, industrially relevant enzymes and nanoparticles.
We are working with evolutionary approaches that could improve genome mining and we explore biochemistry of early cells in relation to the genetic code and establishment of early genomes.
We are organizing the 4th International conference on post-translational modifications in Bacteria in Copenhagen, 16-17 September 2021. PTMBact 2021 conference website.
Prof. Mijakovic is coordinator of an EU ITN consortium “PEST-BIN” – working on new methods to fight bacterial infections.
IMPORTANT NOTE FOR STUDENTS APPLYING FOR INTERNSHIPS:
Please note that our group does not admit internships/student projects shorter than one semester (5-6 months). Master projects carried out in our laboratory are not remunerated, so international students have to secure their own scholarships before applying.
Current members of the Mijakovic Lab:
Lei Shi, researcher
Santosh Pandit, researcher
Abderahmane Derouiche, Post-doc
Shadi Rahimi, Post-doc
Yanyan Chen, Post-doc
Avlant Nilsson, Post-doc
Caroline Wasén, Post-doc
Mahdis Noori, visiting PhD student
Current Members of the Mijakovic lab at DTU Biosustain:
Carsten Jers, senior researcher
Priyanka Singh, Post-doc
Vaishnavi Ravikumar, Post-doc
Abhroop Garg, Post-doc
Mériem Senissar, Post-doc
Julie Bonne Køhler, Post-doc
Abhayraj Joshi, Post-doc
Darko Kjiproski, Project manager
Hossein Helalat, visiting PhD student
Research Associates/Assistant Professors:
Hee Jin Hwang
Mette Erichsen Hansen
Sujata Vijay Sohoni
Visiting PhD students:
Elsebeth Oline Sondergaard
Malene Mejer Hansen
Lorena Kolar Znika